The domain within your query sequence starts at position 1021 and ends at position 1249; the E-value for the 3lxu domain shown below is 1e-20.

FTEALRDLKIQWMTKLDSTDIYNELKETYPAYLPLYVARLHQLDAEKERMKRLNEIVDAA
NAVISHIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLIDALCRKGCALADHLLHTQP
HDGAAAGDAEAKEEEGESTMESLSETYWETTKWTDLFDTKVLIFAYKHALVNKMYGRGLK
FATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMYPPDYCVF

This is a PDB domain - please see the PDBSUM entry of 3lxu for further annotation